COMPOSITION
Each hard gelatin capsule contains:
- Rabeprazole Sodium (Enteric Coated) 20mg
- Domperidone (Sustained Release) 30mg
CLINICAL PHARMACOLOGY
Rabeprazole is a proton pump inhibitor (PPI) that suppresses gastric acid secretion by inhibiting the H+/K+-ATPase pump. Domperidone is a dopamine D2 receptor antagonist that enhances gastrointestinal motility.
INDICATIONS AND USAGE
Used in the treatment of GERD, peptic ulcers, and dyspepsia.on.
CONTRAINDICATIONS
Hypersensitivity to any component. Contraindicated in patients with prolactinoma or gastrointestinal hemorrhage.
PRECAUTIONS
Caution in hepatic impairment, prolonged QT interval, and elderly patients.
DRUG INTERACTIONS
Interacts with ketoconazole, erythromycin, warfarin, and antacids.
PREGNANCY & LACTATION
Use with caution during pregnancy and lactation; consult physician.
DOSAGE AND ADMINISTRATION
One capsule once daily, preferably before breakfast or as directed by a physician.
ADVERSE REACTIONS
Headache, diarrhea, dry mouth, fatigue, and rash.