R-SIV DSR

Rabeprazole Sodium (EC) and Domperidone (SR) Capsules

R SIV DSR

R-SIV_DSR

COMPOSITION

Each hard gelatin capsule contains:
- Rabeprazole Sodium (Enteric Coated) 20mg
- Domperidone (Sustained Release) 30mg

CLINICAL PHARMACOLOGY

Rabeprazole is a proton pump inhibitor (PPI) that suppresses gastric acid secretion by inhibiting the H+/K+-ATPase pump. Domperidone is a dopamine D2 receptor antagonist that enhances gastrointestinal motility.

INDICATIONS AND USAGE

Used in the treatment of GERD, peptic ulcers, and dyspepsia.on.

CONTRAINDICATIONS

Hypersensitivity to any component. Contraindicated in patients with prolactinoma or gastrointestinal hemorrhage.

PRECAUTIONS

Caution in hepatic impairment, prolonged QT interval, and elderly patients.

DRUG INTERACTIONS

Interacts with ketoconazole, erythromycin, warfarin, and antacids.

PREGNANCY & LACTATION

Use with caution during pregnancy and lactation; consult physician.

DOSAGE AND ADMINISTRATION

One capsule once daily, preferably before breakfast or as directed by a physician.

ADVERSE REACTIONS

Headache, diarrhea, dry mouth, fatigue, and rash.

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