DOBESACT

Calcium Dobesilate 500 mg Capsules

DOBESACT

Dobesact

COMPOSITION

Each capsule contains:
- Calcium Dobesilate 500 mg.

CLINICAL PHARMACOLOGY

Calcium Dobesilate reduces capillary permeability and improves venous tone. It inhibits platelet aggregation and reduces blood viscosity. It also enhances nitric oxide synthesis, improving endothelium-dependent relaxation.

INDICATIONS AND USAGE

Used for the treatment of chronic venous insufficiency, hemorrhoidal attacks, diabetic retinopathy, and varicose vein complications.

CONTRAINDICATIONS

Hypersensitivity to calcium dobesilate or any excipients. Severe renal impairment.

PRECAUTIONS

Monitor in patients with known bleeding disorders. Caution in pregnancy and renal dysfunction. Avoid in those with sulfonamide allergy.

DRUG INTERACTIONS

May potentiate the effects of anticoagulants. Monitor INR if used concomitantly.

PREGNANCY & LACTATION

Use only if clearly needed. Caution during lactation as safety data is limited.

DOSAGE AND ADMINISTRATION

500 mg twice daily or as directed by a physician.

ADVERSE REACTIONS

Rash, gastrointestinal discomfort, fever, and rare cases of agranulocytosis.

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