BONWICK 60K

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Cholecalciferol Chewable Tablets 60,000 IU

BONWICK 60K

Bonwick 60K

COMPOSITION

Each chewable tablet contains:
- Cholecalciferol (Vitamin D3) 60,000 IU

CLINICAL PHARMACOLOGY

Cholecalciferol is a fat-soluble vitamin that promotes calcium absorption in the gut and maintains adequate serum calcium and phosphate levels to enable normal mineralization of bone. It also plays a role in immune modulation and cell proliferation.

INDICATIONS AND USAGE

Indicated in the treatment and prevention of Vitamin D3 deficiency, rickets, osteomalacia, and as a supplement in osteoporosis management. Also used in cases of chronic hypoparathyroidism.

CONTRAINDICATIONS

Hypersensitivity to cholecalciferol or any excipient in the formulation. Hypercalcemia, hypervitaminosis D, or malabsorption syndrome.

PRECAUTIONS

Caution in patients with renal impairment, cardiovascular disease, or those receiving digitalis. Monitor serum calcium and phosphate during high-dose therapy.

DRUG INTERACTIONS

Interactions may occur with thiazide diuretics, antiepileptics (phenytoin, phenobarbital), corticosteroids, orlistat, and cholestyramine, reducing efficacy.

PREGNANCY & LACTATION

Vitamin D3 supplementation is often necessary in pregnancy and lactation. Should be administered in recommended doses to avoid fetal hypercalcemia.

DOSAGE AND ADMINISTRATION

- One tablet once weekly for 6-8 weeks, then once monthly as maintenance. Or as directed by a physician.
- Best taken with a fatty meal for optimal absorption.

ADVERSE REACTIONS

Well-tolerated at recommended doses. High doses may cause hypercalcemia, nausea, vomiting, polyuria, and weakness. Rarely, allergic skin reactions may occur.

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